Was working on my old winxp-HDD to clean for backup. until no updates had been made there. was using an older Nvidia-software-version incl. sound.
dont use internal but sound-stick. maybe its software-related. there is a seperate software. will try that again.
have Wireless mouse. tried without prolonged cable both on a multi-pc-switch and cable on MOBO. does not make a difference. removed system-entries and Nvidia-driver/software. didnt help.
Perfect sound on new drive. usb-stick on a power-driven multi-usb-bar. the only device used there.